Samuel Caldwell Alexander (1830–1907) was a nineteenth-century American Presbyterian minister born in Mecklenburg County, North Carolina, who served multiple congregations in the Southern Presbyterian Church. He is best documented as a long-time pastor of churches such as Thyatira and Back Creek, where he was active in preaching, pastoral leadership, and periods of congregational growth. Alexander was also a church historian, authoring published historical addresses and congregational histories that preserved the local and ecclesiastical memory of Southern Presbyterianism.